Infectious Disease and Microbiome Program, Infectious Disease and Microbiome

Marked heterogeneity in malaria infection rate in a Malian longitudinal cohort.

LaVerriere E, Johnson ZM, Shieh M, et al. Marked heterogeneity in malaria infection rate in a Malian longitudinal cohort. Nature communications. 2025;16(1):6512. doi:10.1038/s41467-025-61462-1Google Scholar PubMed DOI

Targeted delivery of diverse biomolecules with engineered bacterial nanosyringes.

Kreitz J, Yang V, Friedrich MJ, Pham J, Macrae RK, Zhang F. Targeted delivery of diverse biomolecules with engineered bacterial nanosyringes. Nature biotechnology. 2025. doi:10.1038/s41587-025-02774-xGoogle Scholar PubMed DOI

Elucidating the role of Campylobacter concisus-derived indole metabolites in gut inflammation and immune modulation.

Park JD, Lee SR, Dhennezel C, et al. Elucidating the role of Campylobacter concisus-derived indole metabolites in gut inflammation and immune modulation. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(34):e2514071122. doi:10.1073/pnas.2514071122Google Scholar PubMed DOI

Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function.

Liu Y, Gu X, Li Y, et al. Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function. Nature medicine. 2025. doi:10.1038/s41591-025-03891-5Google Scholar PubMed DOI

A generative deep learning approach to de novo antibiotic design.

Krishnan A. A generative deep learning approach to de novo antibiotic design. Cell. 2025. doi:10.1016/j.cell.2025.07.033Google Scholar PubMed DOI

Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection.

Das D, Hirayama S, Aye L, et al. Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection. Journal of the National Cancer Institute. 2025. doi:10.1093/jnci/djaf249Google Scholar PubMed DOI

Bead-based approaches for increased sensitivity and multiplexing of CRISPR diagnostics.

Siddiqui SM, Welch NL, Nguyen TG, et al. Bead-based approaches for increased sensitivity and multiplexing of CRISPR diagnostics. Nature biomedical engineering. 2025. doi:10.1038/s41551-025-01498-2Google Scholar PubMed DOI

Insights Into Global Antimicrobial Resistance Dynamics Through the Sequencing of Enteric Bacteria From US International Travelers.

Sridhar S, Worby CJ, Bronson RA, et al. Insights Into Global Antimicrobial Resistance Dynamics Through the Sequencing of Enteric Bacteria From US International Travelers. The Journal of infectious diseases. 2025. doi:10.1093/infdis/jiaf469Google Scholar PubMed DOI

The carbapenem inoculum effect provides insights into the molecular mechanisms underlying carbapenem resistance in the Enterobacterales.

Cartagena AJ, Taylor KL, Lopez LC, et al. The carbapenem inoculum effect provides insights into the molecular mechanisms underlying carbapenem resistance in the Enterobacterales. mBio. 2025:e0154025. doi:10.1128/mbio.01540-25Google Scholar PubMed DOI

Predicting functions of uncharacterized gene products from microbial communities.

Zhang Y, Bhosle A, Bae S, et al. Predicting functions of uncharacterized gene products from microbial communities. Nature biotechnology. 2025. doi:10.1038/s41587-025-02813-7Google Scholar PubMed DOI