Cardiovascular disease

Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass.

Khurshid S, Lazarte J, Pirruccello JP, et al. Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass. Nature communications. 2023;14(1):1558. doi:10.1038/s41467-023-37173-wGoogle Scholar PubMed DOI

Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes.

Halford JL, Morrill VN, Choi SH, et al. Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes. Nature communications. 2022;13(1):5106. doi:10.1038/s41467-022-32009-5Google Scholar PubMed DOI

Monogenic and Polygenic Contributions to QTc Prolongation in the Population.

Nauffal V, Morrill VN, Jurgens SJ, et al. Monogenic and Polygenic Contributions to QTc Prolongation in the Population. Circulation. 2022;145(20):1524-1533. doi:10.1161/CIRCULATIONAHA.121.057261Google Scholar PubMed DOI

Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes.

Halford JL, Morrill VN, Choi SH, et al. Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes. Nature communications. 2022;13(1):5767. doi:10.1038/s41467-022-33534-zGoogle Scholar PubMed DOI

Distribution and medical impact of loss-of-function variants in the Finnish founder population.

Lim ET, Würtz P, Havulinna AS, et al. Distribution and medical impact of loss-of-function variants in the Finnish founder population. PLoS Genet. 2014;10(7):e1004494. doi:10.1371/journal.pgen.1004494Google Scholar PubMed DOI