Obesity

Genetics of sexually dimorphic adipose distribution in humans.

Hansen GT, Sobreira DR, Weber ZT, et al. Genetics of sexually dimorphic adipose distribution in humans. Nature genetics. 2023;55(3):461-470. doi:10.1038/s41588-023-01306-0Google Scholar PubMed DOI

Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b.

Patel SJ, Liu N, Piaker S, et al. Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b. Sci Transl Med. 2022;14(637):eabh3831. doi:10.1126/scitranslmed.abh3831Google Scholar PubMed DOI

Crosstalk Between Adipose and Lymphatics in Health and Disease.

Westcott GP, Rosen ED. Crosstalk Between Adipose and Lymphatics in Health and Disease. Endocrinology. 2022;163(1). doi:10.1210/endocr/bqab224Google Scholar PubMed DOI

Evidence From Men for Ovary-independent Effects of Genetic Risk Factors for Polycystic Ovary Syndrome.

Zhu J, Pujol-Gualdo N, Wittemans LBL, et al. Evidence From Men for Ovary-independent Effects of Genetic Risk Factors for Polycystic Ovary Syndrome. The Journal of clinical endocrinology and metabolism. 2022;107(4):e1577-e1587. doi:10.1210/clinem/dgab838Google Scholar PubMed DOI

Effect of BMI on the Thermogenic Response to Cold Exposure and Associated Changes in Metabolism and Browning Markers in Adult Humans.

Mengel LA, Moud BN, Seidl H, et al. Effect of BMI on the Thermogenic Response to Cold Exposure and Associated Changes in Metabolism and Browning Markers in Adult Humans. Obesity facts. 2022;15(3):405-415. doi:10.1159/000522218Google Scholar PubMed DOI

A single-cell atlas of human and mouse white adipose tissue.

Emont MP, Jacobs C, Essene AL, et al. A single-cell atlas of human and mouse white adipose tissue. Nature. 2022;603(7903):926-933. doi:10.1038/s41586-022-04518-2Google Scholar PubMed DOI

Transcriptome and fatty-acid signatures of adipocyte hypertrophy and its non-invasive MR-based characterization in human adipose tissue.

Honecker J, Ruschke S, Seeliger C, et al. Transcriptome and fatty-acid signatures of adipocyte hypertrophy and its non-invasive MR-based characterization in human adipose tissue. EBioMedicine. 2022;79:104020. doi:10.1016/j.ebiom.2022.104020Google Scholar PubMed DOI

Post-translational control of beige fat biogenesis by PRDM16 stabilization.

Wang Q, Li H, Tajima K, et al. Post-translational control of beige fat biogenesis by PRDM16 stabilization. Nature. 2022;609(7925):151-158. doi:10.1038/s41586-022-05067-4Google Scholar PubMed DOI

Linking the obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo.

Laber S, Forcisi S, Bentley L, et al. Linking the obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo. Science advances. 2021;7(30). doi:10.1126/sciadv.abg0108Google Scholar PubMed DOI

Mesothelial cells are not a source of adipocytes in mice.

Westcott GP, Emont MP, Li J, Jacobs C, Tsai L, Rosen ED. Mesothelial cells are not a source of adipocytes in mice. Cell reports. 2021;36(2):109388. doi:10.1016/j.celrep.2021.109388Google Scholar PubMed DOI