Proteomics Platform

Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.

Hsu YHH, Pintacuda G, Liu R, et al. Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia. iScience. 2023;26(5):106701. doi:10.1016/j.isci.2023.106701Google Scholar PubMed DOI

Proteomic profiling of extracellular matrix components from patient metastases identifies consistently elevated proteins for developing nanobodies that target primary tumors and metastases.

Jailkhani N, Clauser KR, Mak HH, et al. Proteomic profiling of extracellular matrix components from patient metastases identifies consistently elevated proteins for developing nanobodies that target primary tumors and metastases. Cancer research. 2023. doi:10.1158/0008-5472.CAN-22-1532Google Scholar PubMed DOI

Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells.

Lee SY, Cheah JS, Zhao B, et al. Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.09.531939Google Scholar PubMed DOI

Chromatin regulator SMARCAL1 modulates cellular lipid metabolism.

Nagai TH, Hartigan C, Mizoguchi T, et al. Chromatin regulator SMARCAL1 modulates cellular lipid metabolism. Communications biology. 2023;6(1):1298. doi:10.1038/s42003-023-05665-6Google Scholar PubMed DOI

ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer.

Mota I, Patrucco E, Mastini C, et al. ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer. Nature cancer. 2023. doi:10.1038/s43018-023-00591-2Google Scholar PubMed DOI

Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset.

Mansur A, Joseph R, Kim E, et al. Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset. eLife. 2023;12. doi:10.7554/eLife.81966Google Scholar PubMed DOI

Dynamic mapping of proteome trafficking within and between living cells by TransitID.

Xu W, Cheah J, Xu C, et al. Dynamic mapping of proteome trafficking within and between living cells by TransitID. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.02.07.527548Google Scholar PubMed DOI

ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling.

Gentili M, Liu B, Papanastasiou M, et al. ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling. Nature communications. 2023;14(1):611. doi:10.1038/s41467-023-36132-9Google Scholar PubMed DOI

An automated nanowell-array workflow for quantitative multiplexed single-cell proteomics sample preparation at high sensitivity.

Ctortecka C, Hartlmayr D, Seth A, et al. An automated nanowell-array workflow for quantitative multiplexed single-cell proteomics sample preparation at high sensitivity. Molecular & cellular proteomics : MCP. 2023:100665. doi:10.1016/j.mcpro.2023.100665Google Scholar PubMed DOI

The HLA-II immunopeptidome of SARS-CoV-2.

Weingarten-Gabbay S, Chen DY, Sarkizova S, et al. The HLA-II immunopeptidome of SARS-CoV-2. Cell reports. 2023;43(1):113596. doi:10.1016/j.celrep.2023.113596Google Scholar PubMed DOI